• After the success of the Millennium Development

  2019-06-24

  

  After the success of the Millennium Development Goals and the reduction in more than 50% of child mortality in children younger than 5 years (Countdown to 2015 report), the survive and thrive motto was given prominence by the Sustainable Development Goals (SDGs). For all children to thrive, we need

• Numbers studies also showed that the MSCs

  2019-06-24

  

  Numbers studies also showed that the MSCs have the capacity to differentiate into multiple mesenchymal tissues both in vitro and in vivo, including osteoblast [25,34], condrocyte [35,36], adipocyte [37,38], tendon [39,40], skeletal muscle cells [39], cardiomyocyte [41,42] and hematopoietic supportin

• br Other drugs Overdose of diphenhydramine an

  2019-06-24

  

  Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium WM-8014 and thus to unmask a BrS phenotype [60]. Alcoho

• For HL most previous studies have shown a correlation

  2019-06-24

  

  For HL, most previous studies have shown a correlation between decreasing survival rates for patients with HL with decreasing SES, although several studies found no or a varied association between survival outcomes in patients with HL with decreasing SES. The differences in these findings may be att

• Apart from their association with severe pain and

  2019-06-24

  

  Apart from their association with severe pain and reduced quality of life, SREs require substantial healthcare resource utilization (HRU) in their treatment and management. Previous retrospective studies have attempted to quantify various aspects of the burden of SREs across specific tumor types/cou

• br Genetic basis for atrial standstill br Genetic

  2019-06-24

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

• Gender transformative policy and cultural reforms are also

  2019-06-24

  

  Gender transformative policy and cultural reforms are also crucial to change prevailing norms and customs that devalue women and girls. Implementation and enforcement of non-discriminatory policies and practices that require gender equity in inheritance, property rights, education, and civil liberti

• br An estimated million babies

  2019-06-24

  

  An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve

• Sin embargo las identidades sexuales politizadas no han

  2019-06-24

  

  Sin embargo, las identidades sexuales politizadas no han sido simples corolarios de la homofobia y trato despectivo hacia las sexualidades contra culturales. Para hacerse visibles, requirieron complejas condiciones sociales y políticas con el fin de producir un sentido de experiencia de comunidad qu

• Obesity is not the only concern documented for

  2019-06-24

  

  Obesity is not the only concern documented for BPA. Epidemiological studies have identified neurocognitive effects of BPA and newly incident coronary artery disease, and laboratory studies strongly suggest BPA is an ovarian toxicant. The rapidly rising evidence of adverse effects has prompted manufa

• Interpretation Patient centred medical education can improve

  2019-06-24

  

  Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei

• What lies ahead Clearly the extremely ambitious goals and ta

  2019-06-24

  

  What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy

• br Relationship among ICD shocks substrate and mortality The

  2019-06-24

  

  Relationship among ICD shocks, substrate, and mortality There is a strong correlation between ICD-shocked spontaneous VTAs and subsequent mortality [5,6]. Patients who receive inappropriate shocks are also at an increased risk of mortality, although the magnitude of this increase is smaller [5,6]

• br Conclusions It is now

  2019-06-21

  

  Conclusions It is now clear that a number of Moxidectin are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucidated; these genet

• br A tactical change in

  2019-06-21

  

  A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di

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