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Studies into regulation of p via PTM processes that involve
2020-07-31
Studies into regulation of p53 via PTM processes that involve phosphorylation, acetylation, ubiquitination, SUMOylation, neddylation, and methylation are being increasingly reported [23], [24]. Phosphorylation and acetylation of p53 stimulate p53-associated transcription factors [25], [26], whereas
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Similarly high quantities of DNA were recovered
2020-07-31
Similarly high quantities of DNA were recovered from the laundered fmoc osu synthesis stains, regardless of wash temperature, detergent used, material type, or number of washes, although very varied results were obtained (Fig. 1, Fig. 2). Wash conditions and type of material have previously been fo
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With regard to neuroticism anxiety
2020-07-31
With regard to neuroticism/anxiety we did not find any direct associations with conditioned fear responses, which converges with a series of previous studies (Fredrikson and Georgiades, 1992, Grillon et al., 2006, Joos et al., 2012, Lommen et al., 2010, Martínez et al., 2012, Otto et al., 2007, Pine
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Bazedoxifene HCl receptor In conclusion our results demonstr
2020-07-30
In conclusion, our results demonstrate that CCLP promoted osteoblast proliferation, differentiation, and mineralization via activation of ERK, p38, and Smad1/5/8 (Fig. 9). The residues of the GGKQNVGFGP-sequence in CCLP showed the highest significant binding relationship with the target activin rece
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We were able to select a
2020-07-30
We were able to select a small single crystal of the orange material from among the original red crystals. The small crystal only diffracted weakly but we were able to obtain a crystal structure, albeit of lower quality than that of the red form. The structure is not too dissimilar to that of the re
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In rat liver a minimum of of the TAG incorporated
2020-07-30
In rat liver, a minimum of 60% of the TAG incorporated into VLDL originates from stored hepatic TAG rather than direct transfer of de novo synthesized TAG on the cytoplasmic side of the ER membrane [5]. This stored hepatic TAG includes exogenous TAG from chylomicron remnants derived from the diet, a
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In maize embryo axes tissues the
2020-07-30
In maize embryo axes tissues, the co-elution of PCNA together with CycD3;1 and CDKs in high molecular mass fractions that vary in size along the germination process was indicative of a possible and probably dynamic association to proteins, being the variation in molecular mass due to the association
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Chromosome region maintenance CRM is the
2020-07-30
Chromosome region maintenance-1 (CRM1) is the only nuclear exporter protein in the karyopherin-β protein family that contributes to the trafficking of numerous proteins, including tumor suppressor, growth regulator/pro-inflammatory and anti-apoptotic proteins, and RNAs essential for ribosomal biogen
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br Involvement of p and Sp To investigate
2020-07-30
Involvement of p53 and Sp1 To investigate transcriptional regulation of the COX-2 gene in response to HNE, Kumagai et al. [15] examined whether the HNE-induced COX-2 expression was mechanistically linked to the expression of p53, a transcription factor that regulates the response to a variety of
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br Material and methods br Discussion First we investigated
2020-07-30
Material and methods Discussion First, we investigated cannabis use, and results showed that the lifetime prevalence of cannabis use in our sample was 29.63%, with a significant difference between males (73.8% of the abusers) and females (26.2%). Moreover, the mean age and age at onset were si
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The TAG inserted pattern is likely the
2020-07-30
The TAG-inserted pattern is likely the cause of myotonia, as it produces a stop Anidulafungin mg just before exon 7 and can suppress the expression of the 5–6–7 splicing pattern. Although we detected the acceptor site responsible for this insertion, the overall function of the TAG-inserted pattern
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br Conclusions br Conflict of interest br Acknowledgements T
2020-07-29
Conclusions Conflict of interest Acknowledgements The authors are supported by National Institutes of Health grants (CA162804, CA92584, and CA13499 to DJC and CA166677 to BPPC) and Cancer Prevention and Research Institute of Texas (RP110465 to DJC). The cellular response to DNA double-st
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Convergent reports indicate that the activation of medullary
2020-07-29
Convergent reports indicate that the activation of medullary TRH pathways plays a physiological role in autonomic mediated visceral responses to an acute cold stress [1], [18] that can be mimicked by the ic injection of TRH or analog [32]. The demonstration that iv hUcn II-induced hypotension while
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br Transparency document br Introduction Nanosecond electric
2020-07-29
Transparency document Introduction Nanosecond electric pulses (nsEP) evoke a high voltage in specific cellular structures without producing any heat, thereby triggering responses such as membrane poration and DNA damage [1], [2], [3]. nsEP can be used to enhance chemotherapy and ablate tissues
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Experimental errors should be analyze since they could justi
2020-07-29
Experimental errors should be analyze since they could justify the deviation between predicted and experimental data. Error experimental for solubility data in ternary and quaternary systems were not reported in detail (for each point) in most solubility data sources used in our work. Excluding the
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