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The studies from several laboratories suggest that
2019-04-22
The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi
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In our study acute toxicities were mild and there
2019-04-22
In our study, acute toxicities were mild, and there were no Grade 3 or above hematologic toxicities. Only one patient (3.2%) had Grade 3 esophagus toxicity and three patients (9.7%) had Grade 3 lung toxicity. Compared with studies that investigated regimens of oxaliplatin and 5-FU/leucovorin, the pr
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br Sustained monomorphic ventricular tachycardia br Monomorp
2019-04-22
Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr
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Some patients developed osmotic demyelination disease ODS
2019-04-22
Some patients developed osmotic demyelination disease (ODS) after rapid correction of hyponatremia. Predisposing factors to development of ODS were syndrome of inappropriate antidiuretic hormone, alcoholism, liver cirrhosis, liver transplantation, renal failure, burns, malnutrition, or neoplasm. Oth
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Based on the methodology used in
2019-04-22
Based on the methodology used in previous studies, the EGM source for the Wavelet algorithm has been nominally programmed as the Can-RV coil EGM [13]. As the nominal EGM source includes the generator, myopotentials induced due to body motion or other muscle activity are likely to influence the arrhy
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Preference for injectable therapy over oral therapy contrary
2019-04-22
Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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br Discussion Furthermore most of the previously described c
2019-04-22
Discussion Furthermore most of the previously described cases with a solitary lesion affecting bone involved the craniofacial bones [2–7], and only a few cases affected the appendicular skeleton. Several affected extra-craniofacial sites have been sporadically reported, for example: femur [8], ti
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The greater relative importance of indirect causes could be
2019-04-22
The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment
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br El Movimiento Espa ol ha sido
2019-04-22
El Movimiento Español 1959, ha sido definido por Eduardo Mateo Gambarte como: “el último latido de los más jóvenes exiliados por incorporarse order Wnt agonist 1 la lucha antifranquista”. Pese a su limitado número de participantes y su corto recorrido, representó un fenómeno destacable al estar en
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Menci n aparte merecen dos rasgos en la
2019-04-22
Mención aparte merecen dos rasgos en la construcción de este personaje y de su entorno: en primer lugar, sufre de una úlcera en el duodeno que lo hace beber leche en múltiples momentos o mitigar el dolor masticando antiácidos Pepsamar. Mattos se está consumiendo por dentro, en una metáfora que utili
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br Basis and methodology of DCE MRI
2019-04-20
Basis and methodology of DCE-MRI DCE-MRI images are performed by using injecting low-molecular-weight gadolinium chelated contrast agent with a constant, stable rate. The contrast agent is carried by blood flow into the tissue, causing increased signal intensity (SI) of the T1-weighted images due
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br Postoperative rehabilitation Although surgery is the main
2019-04-20
Postoperative rehabilitation Although surgery is the main curative therapy for lung cancer, the procedure can directly cause a reduction in pulmonary functional reserve and exercise capacity proportional to the extent of resection. The problems might be more severe in those undergoing multimodali
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purchase EZ Cap Reagent AG (3\' OMe) Early repolarizatio
2019-04-20
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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Two years later he complained of two
2019-04-20
Two years later, he complained of two ICD shocks during a dance party. The possibility of lead fracture or electromagnetic interference was completely excluded after several examinations. Intracardiac electrograms showed that all delivered shocks were inappropriate therapies due to TWOS. The R wave
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will be remembered as an exceptional year in shaping our
2019-04-20
2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi
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