• Introduction Atrial fibrillation AF is a highly prevalent at

  2019-05-20

  

  Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF

• br Methods We described our strategies for

  2019-05-20

  

  Methods We described our strategies for ablating AF in previous reports [34–36]. Therefore, we will discuss our methods for CFAE ablation, including CFAE-ablation combined with PVI, below. Results Representative cases of CFAE-ablation Conclusions Acknowledgments Characteristics of

• br Study limitations br Introduction The spread of

  2019-05-20

  

  Study limitations Introduction The spread of basic life support (BLS), including use of automated external defibrillators in the general public, may increase the chance of survival from sudden cardiac death (SCD). Survivors usually have underlying cardiac diseases, such as coronary artery dise

• br Conflict of interest br Introduction Bladder

  2019-05-20

  

  Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of herpes simplex virus 1 cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men and in the el

• br The L type calcium channel

  2019-05-18

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• Primary lymphoma of bone is an uncommon clinical

  2019-05-18

  

  Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and h

• In this study we applied a more

  2019-05-18

  

  In this study, we applied a more general approach along these lines, which has previously been used only in few reports in the literature [8]. Based on a prospective BC database including all newly diagnosed BC cases at a large Swiss breast center over a 20-year period, we aimed to give a comprehens

• protease inhibitor cocktail Bepridil is a multichannel block

  2019-05-18

  

  Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K protease inhibitor cocktail

• br Discussion In Brugada syndrome

  2019-05-18

  

  Discussion In Brugada syndrome (BrS), ICD sigma 1 receptor is recommended for patients experiencing VF. However, up to 48% of such high-risk patients experience frequent ICD shocks [1] that result in significant sequelae such as depression, post-traumatic stress, and difficult VF termination due

• br Health research consortia in sub

  2019-05-18

  

  Health research consortia in sub-Saharan Africa present a positive outlook for the region through increased scientific capacity. New networks of African–African, African–European, and African–global partnerships provide platforms to advance crucial research domains. Such networks enable junior Afr

• br Drug resistant tuberculosis threatens to

  2019-05-18

  

  Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat

• An incisional biopsy was undertaken Peri operative examinati

  2019-05-17

  

  An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material

• Nademanee et al reported nine

  2019-05-17

  

  Nademanee et al. reported nine symptomatic patients with BrS who experienced VF and underwent electrophysiological study and catheter ablation [8]. The patients exhibited abnormal epicardial electrograms characterized by fragmented electrograms with a relatively low voltage ( Idiopathic ventricular

• There is strong agreement that HIV

  2019-05-17

  

  There is strong agreement that HIV prevention should focus on approaches that are evidence based, but there is disagreement about how to obtain such rigorous evidence and whether this should refer only to randomised study designs. Pickles and colleagues\' report provides a concrete example of an eff

• Transformation of sanitation related knowledge into routine

  2019-05-17

  

  Transformation of sanitation-related knowledge into routine practice is hindered by traditional mindsets and the absence of awareness and an attitude to learn. Poverty has been described as a barrier to following safe hygiene practices. Regular use of footwear is equally important for the prevention

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